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FoundMyFitness

Rhonda Patrick, Ph.D.
FoundMyFitness
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  • #106 How To Increase Your Testosterone Levels Naturally | Derek from MPMD
    Get access to more than 70 Ask Me Anything episodes with Dr. Rhonda Patrick when you sign up as a FoundMyFitness Premium Member When testosterone runs low, libido isn’t the only casualty—muscle mass drops, fat accumulates, insulin resistance rises, and motivation declines. In this episode, Derek from More Plates More Dates highlights common pitfalls that suppress testosterone and evaluates popular testosterone-boosting supplements like Tongkat Ali, boron, and ashwagandha, clarifying what's evidence-based versus overhyped. He also details practical strategies for testosterone replacement therapy (TRT), covering optimal delivery methods, benefits, risks, fertility implications, and key biomarkers to monitor. Timestamps: (00:00) Introduction (04:50) Why is testosterone essential for men? (07:11) The role of testosterone in women’s health (08:53) Does higher testosterone shorten lifespan? (12:12) What the castrati reveal about testosterone and longevity (15:07) Free vs. total testosterone—what’s the difference? (18:42) Best practices for measuring and interpreting testosterone levels (21:29) Reference ranges or symptoms—which matters more? (24:50) When is high testosterone a red flag? (26:32) What LH and FSH reveal about testosterone production (31:11) Could high SHBG levels be limiting your testosterone? (35:02) Why SHBG increases with age—and how diet and lifestyle accelerate it (39:45) Key symptoms of low testosterone in men (42:46) Is alcohol sabotaging your testosterone levels? (45:39) Why low-fat and low-carb diets might lower testosterone (46:18) Common micronutrient mistakes hurting hormone levels (48:12) How excess body fat impacts testosterone (51:39) When endurance training goes too far (56:02) Are endocrine disruptors truly harming male hormones? (58:42) Debunking myths about declining testosterone in men (1:01:32) Why dietary fat is essential for hormone health (1:03:55) Is a ketogenic diet bad for testosterone? (1:05:10) Which type of exercise boosts testosterone most? (1:07:16) Do vitamin D, zinc, and magnesium actually help? (1:11:36) Does boron significantly raise free testosterone? (1:12:45) Ashwagandha’s true potential for testosterone enhancement (1:17:00) Is Tongkat Ali the best herbal testosterone booster? (1:20:51) Tongkat Ali or boron—which is superior? (1:22:20) Shilajit, Tribulus, Fenugreek—do they actually work? (1:23:33) The four best supplements to raise testosterone levels (1:25:17) Dutch test vs. blood test—which is better for cortisol? (1:26:32) When should you consider testosterone replacement therapy (TRT)? (1:34:23) What realistic benefits can TRT provide? (1:37:34) Does TRT raise heart disease and erythrocytosis risk? (1:47:23) Creams vs. injections (1:48:47) Does TRT increase prostate cancer risk? (1:51:01) Hair loss, acne, sleep apnea—what are TRT’s real side effects? (1:53:41) The rollercoaster effect of testosterone injections (1:56:15) Could low testosterone be riskier than TRT? (1:59:38) Choosing the right TRT delivery method (2:06:16) Do smaller, more frequent injections reduce risks? (2:08:12) Can you maintain fertility while on TRT? (2:16:12) Why TRT quickly shrinks testicles (2:17:40) Key biomarkers you must track on TRT (2:26:57) Testosterone therapy for women—symptoms, ranges, and risks (2:36:49) Can DHEA supplements safely raise testosterone in women? (2:39:47) What actually causes hair loss? (2:46:00) Does your maternal grandfather determine your hairline? (2:46:48) Why stopping hair loss means accepting risks (2:55:54) How effective are ketoconazole, minoxidil, and microneedling? (2:58:55) Topical vs. oral minoxidil—how do side effects compare? (3:02:00) Is microneedling effective without minoxidil? (3:04:51) Do finasteride and dutasteride alter brain chemistry? (3:06:03) Finasteride and the nocebo effect—are side effects imagined? (3:07:37) Does minoxidil delay baldness or just mask it? (3:09:06) Can dutasteride extend your lifespan? Show notes, transcript, and summary are available by clicking here Watch this episode on YouTube  
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  • #105 Exogenous ketones, my coffee protocol, and supplements for blood sugar regulation (Premium Member Q&A July 2025)
    Become a FoundMyFitness Premium Member to access the full episode In this special episode, you'll get an exclusive 30-minute preview of my latest Ask Me Anything (AMA) session, normally reserved for FoundMyFitness Premium Members. Each month, Premium Members join me live to receive direct answers to their most pressing questions on nutrition, supplements, longevity, sleep, fitness—no topic is off-limits. In today's sneak peek, you'll hear why I've started taking exogenous ketones, details about my personal coffee routine (from bean choices to brewing methods), optimal supplement dosages (including ubiquinol, berberine, and vitamin K2), and whether some popular greens powders might pose risks due to heavy metals. Learn more here about becoming a FoundMyFitness Premium Member for as little as $15 per month. After signing up, you'll also unlock the full 90-minute session, along with more than 100 hours of additional AMA content. Your membership directly supports our mission to deliver trustworthy, unbiased, science-backed health information that's entirely ad-free and free from commercial bias. Every Premium Member helps us stay focused solely on providing you with the highest-quality insights grounded in rigorous science. Timestamps: (00:00) Introduction (02:44) Why I started taking exogenous ketones (04:02) What ketone supplement brand am I using? (07:16) Can ketones help reduce performance anxiety? (08:50) My daily coffee routine (beans, brewing, and tips) (11:31) Should you worry about diterpenes in coffee? (12:56) Which coffee bean brand do I trust most? (14:04) Does coffee cause dehydration or block mineral absorption? (15:46) Is drinking coffee on an empty stomach harmful? (16:01) Does dairy reduce coffee’s polyphenol benefits? (17:53) Should slow caffeine metabolizers avoid coffee? (18:52) Can coffee’s vasoconstriction affect brain blood flow? (19:18) Do coffee pods release harmful microplastics? (20:09) The ketone meter I've relied on for 10 years (20:35) Does quitting caffeine lower resting heart rate? (20:41) What's the best plastic-free coffee maker? (21:13) Ideal dosing for ubiquinol, berberine, and alpha-lipoic acid (22:43) Which supplements best support fertility and egg quality? (23:49) Why (and how much) myo-inositol did I take? (24:08) Am I still taking benfotiamine, collagen, lutein, and zeaxanthin? (24:34) Creatine vs. methylated B vitamins for homocysteine control (25:56) Which vitamin K2 supplement (and dosage) do I use? (26:17) Are greens powders (like moringa) high in heavy metals? (27:16) Which choline supplement won't raise TMAO? (30:31) Which Thorne supplements do I personally use? (30:44) How much CoQ10 is needed if you're not targeting fertility?
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  • #103 A Deep Dive on Using Coffee For Health & Longevity (Full Guide & Research)
    Get access to more than 120 episodes of my premium podcast, The Aliquot, as a FoundMyFitness Premium Member Coffee is one of the most powerful longevity tools we have, potentially reducing epigenetic age by up to one year in regular coffee drinkers, but its effectiveness hinges entirely on how you brew it. In this episode, I outline precisely how coffee reduces DNA damage, a key driver of cancer and cellular aging, and why choosing filtered coffee over methods like French press significantly lowers cholesterol risk. I’ll discuss exactly which beans and roasts pack the highest antioxidant punch, plus a practical tip on a specific supplement that amplifies coffee’s cognitive benefits. You’ll also learn the truth about mycotoxins in coffee and why adding dairy can blunt coffee’s immediate cognitive-boosting effects. Timestamps: (00:00) Introduction (01:24) Can coffee really slow biological aging? (04:42) Is coffee actually protective for your heart? (05:27) Why morning coffee is healthier than afternoon coffee (08:01) How coffee improves your metabolic health (09:52) Can coffee reduce cancer risk? (11:25) Does coffee protect DNA from damage? (13:38) Can coffee enhance your gut microbiome? (16:01) Can unfiltered coffee raise your cholesterol? (20:13) Which brewing method maximizes antioxidants? (20:40) Arabica or robusta—does bean type matter? (23:04) Dark vs. light roast—what’s richer in antioxidants? (23:28) Is cold brew coffee as healthy as hot coffee? (23:51) Practical tips to maximize antioxidants (24:38) Filtered vs. French press—what’s best for longevity? (26:48) Can espresso’s antioxidants offset its cholesterol risk? (27:18) Instant coffee—an overlooked longevity booster? (27:40) Why filtered coffee is the clear winner (28:20) Caffeinated vs. decaf—what’s better for your brain? (30:42) Can decaf coffee still enhance cognitive function? (33:38) How much caffeine is optimal for athletic performance? (36:31) How decaffeination methods affect coffee’s benefits (39:02) Are mold toxins in coffee really a concern? (41:45) Is adding dairy a mistake? (43:15) Does MCT powder boost cognition—or just cholesterol? (44:59) Does adding L-theanine reduce caffeine-induced anxiety? (47:04) The science-backed coffee routine for longevity Show notes, transcript, and summary are available by clicking here Watch this episode on YouTube
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  • #102 Why Vitamin D Deficiency Accelerates Brain Aging
    Discover my premium podcast, The Aliquot Vitamin D is far more than just a vitamin—it's a potent steroid hormone regulating nearly 5% of our genome. Yet, remarkably, up to 70% of Americans aren't getting enough, placing them at increased risk for dementia and Alzheimer's disease. In this episode, I explore compelling new evidence from a study involving over 12,000 participants, demonstrating that vitamin D supplementation can reduce dementia risk by an impressive 40%, protecting even adults with genetic Alzheimer's risk (ApoE4 carriers). Timestamps: (00:00) Can vitamin D supplements reduce dementia risk? (00:46) How common is vitamin D deficiency? (03:31) What studies reveal about genes, vitamin D, and dementia (05:44) Does deficiency accelerate brain aging? (06:45) Can vitamin D supplementation enhance cognitive function? (08:15) Dementia risk reduction insights from 12,388 adults (09:58) Why women may benefit most (10:49) Normal vs. impaired cognition—who benefits more from vitamin D? (11:21) Do ApoE4 carriers get dementia protection from vitamin D? (13:00) How mild cognitive impairment affects dementia risk (13:41) Does the form of vitamin D matter? (14:11) What are the optimal vitamin D blood levels? (15:07) What dose corrects deficiency? (15:33) How vitamin D directly supports brain function Watch this episode on YouTube Show notes are available by clicking here The study discussed: Vitamin D supplementation and incident dementia: Effects of sex, APOE, and baseline cognitive status
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  • #101 Dr. Andy Galpin: The Optimal Diet, Supplement, & Recovery Protocol for Peak Performance
    Download my “How to Train According to the Experts” guide Discover my premium podcast, The Aliquot Nutrition, supplementation, and recovery are foundational for enhancing exercise performance, but their full potential often remains untapped. In this episode, Dr. Andy Galpin, a renowned expert who has coached Olympians, world champions, and professional athletes across major sports, breaks down exactly how to leverage these critical elements to meaningfully enhance your results.  Timestamps: (00:00) Introduction (05:01) Eating to perform vs. eating to live longer—do you have to choose? (08:20) Training fasted—are the mitochondrial benefits worth it? (14:53) What should you eat before early-morning strength training? (16:52) Why nutrient timing isn't critical for the average exerciser (18:44) Is intermittent fasting killing your gains? (29:24) Carbs before resistance training—fuel or fluff? (31:07) Endurance fueling strategies—what actually works? (36:02) When is post-exercise carb intake truly essential? (37:35) Game day fueling—how to get it right (40:25) Carb supplements vs. whole foods—what do elite athletes actually eat? (43:18) Rethinking fat intake for exercise performance (46:14) Metabolic flexibility—how the term got hijacked (50:39) The real test of metabolic health—why skipping a meal shouldn't break you (51:55) Are anaerobic and aerobic systems truly separate? (55:56) Does protein timing really matter? (58:27) Whole foods vs. protein powders (1:03:21) Fat timing—overlooked or irrelevant? (1:04:48) The truth about seed oils and saturated fat (1:09:43) Magnesium—who actually needs to supplement? (1:11:43) The problem with magnesium blood tests (1:13:01) Why the magnesium RDA might not be enough (1:13:54) Magnesium citrate, glycinate, or threonate—does it matter? (1:15:55) Do magnesium supplements really aid recovery? (1:18:35) Omega-3 supplementation—is the AFib risk real? (1:22:10) Can omega-3s prevent muscle loss during inactivity? (1:26:14) Why "performance anchors" matter more than supplements (1:30:47) Iron deficiency—the hidden performance killer? (1:33:42) Does caffeine before workouts increase fat burning? (1:35:29) Caffeine cycling—smart strategy or outdated myth? (1:38:45) Can music measurably enhance workout performance? (1:39:57) Rhodiola rosea—fatigue fighter or placebo? (1:44:38) Beetroot, citrulline, arginine—do nitric oxide boosters work? (1:55:07) Beta-alanine—why the tingles might be worth it (2:01:05) Is 5g of creatine really enough? (2:02:18) Sodium bicarbonate—effective fatigue buffer or GI nightmare? (2:04:36) Can you trust what's in your pre-workout supplement? (2:06:54) Is too much caffeine killing your performance gains? (2:07:41) Can antioxidants blunt exercise performance? (2:08:40) High-dose vitamin C—immune protection or adaptation killer? (2:15:12) Do anti-inflammatories sabotage your gains? (2:17:38) Tart cherry juice—recovery aid or overhyped? (2:21:04) Is glutamine the immune booster athletes need? (2:29:11) Can collagen actually strengthen tendons? (2:33:26) Does glucosamine chondroitin actually help joints? (2:34:28) What really happens during recovery—signaling vs. inflammation (2:37:25) The most important recovery metric (2:39:05) How increased blood flow accelerates muscle repair (2:43:55) Why persistent soreness might mean your fascia's at fault (2:47:02) Can compression boots genuinely speed recovery? (2:47:56) Can simply soaking in water accelerate recovery? (2:51:13) When is sauna a better choice than extra miles? (2:53:12) Can localized heat preserve muscle during downtime? (2:54:31) Cold immersion timing—muscle recovery vs. blunting gains (3:01:16) Why pre-bed cold exposure might improve sleep (3:04:31) Heart rate variability vs. resting heart rate (3:12:45) Why respiratory rate predicts stress better than resting heart rate (3:16:57) Are you overtrained—or just overreached? (3:21:41) Hormones and overtraining—what's the real link? (3:25:48) Does training harder mean you need more sleep? (3:27:54) How to know if you're getting enough sleep (3:31:17) Sleep trackers (3:33:10) Hydration timing—the key to uninterrupted sleep? (3:34:54) Why your wind-down index matters (3:36:02) Is your bedroom's CO₂ buildup sabotaging your sleep? (3:39:40) Are nasal allergies quietly wrecking your recovery? (3:41:23) Sleep hacks—what actually works? Watch this episode on YouTube Show notes are available by clicking here
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