Infectious Disease Puscast

On episode #103 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/12 – 3/25/26.
Host: Daniel Griffin and Sarah Dong
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Links for this episode
Viral
Probable Japanese Encephalitis Virus Transmission through Organ Transplantation (NEJM)
Clinical Characteristics and Severity of Rhinovirus/Enterovirus–Associated Hospitalizations: A Multi-country Analysis from the Global Influenza Hospital Surveillance Network, 2017–2024 (OFID)
Bacterial
Eagle effect (Wikipedia)
THE RATE OF BACTERICIDAL ACTION OF PENICILLIN IN VITRO AS A FUNCTION OF ITS CONCENTRATION, AND ITS PARADOXICALLY REDUCED ACTIVITY AT HIGH CONCENTRATIONS AGAINST CERTAIN ORGANISMS (JEM)
Linezolid versus clindamycin for toxin inhibition in severe skin and soft tissue infections: a systematic review and meta-analysis (Infection)
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026 (Critical Care Medicine)
Caring for Adult Patients With Sepsis (JAMA)
Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026 (Intensive Care Medicine)
Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026 (Pediatric Critical Care Medicine)
Caring for Pediatric Patients With Sepsis (JAMA)
ACEP Will Not Endorse New Sepsis Guidelines from the Surviving Sepsis Campaign (American College of Emergency Physicians)
Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With SepsisThe BLING III Randomized Clinical Trial (JAMA)
Activation of l-histidine biosynthesis as a new antibiotic strategy against Mycobacterium tuberculosis (Nature Communications)
Survival trends in patients with difficult-to-treat, antibiotic-resistant, Gram-negative infections in the era of next-generation antibiotics in the USA: a retrospective cohort study (LANCET: Infectious Diseases)
Fungal
The Last of US Season 2 (YouTube)
Empirical Antifungal Treatment of Critically Ⅲ Patients With Influenza-Associated Acute Respiratory Distress Syndrome: A Propensity Score Weighted Observational Study (CID)
Clinical and Radiological Predictors of Invasive Fungal Sinusitis (OFID)
Blood Cultures Contain Populations of Genetically Diverse Candida albicans Strains that May Differ in Echinocandin Tolerance and Fitness (JID)
Can fluconazole be used to treat non-resistant Candida (Candidozyma) auris infections? Preclinical PK/PD data from a Galleria mellonella infection model (JID)
Parasitic
Na-GST-1 adsorbed on Alhydrogel co-administered with different Toll-like receptor agonists in hookworm-naive adults using a controlled human infection model in the USA: a phase 2, double-blind, randomised controlled trial (LANCET: Infectious Diseases)
Miscellaneous
Bridging the Gap: A Needs Assessment of Resources and Support for International Medical Graduates Navigating Visa-Related Career Decisions in Infectious Diseases (OFID)
Number Needed to Treat (NEJM)
Music is by Ronald Jenkees
Information on this podcast should not be considered as medical advice.

On episode #102 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/26 – 3/11/26.
Host: Daniel Griffin and Sarah Dong
Subscribe (free): Apple Podcasts, RSS, email
Become a patron of Puscast!
Links for this episode
Viral
Measles Outbreak — New Mexico, 2025 (CDC: MMWR)
Epidemiology of HMPV and Other Respiratory Viral Infections Among Outpatients, 2016–2022 (OFID)
Notes from the Field: Congenital Rubella Syndrome — Florida, 2025 (CDC: MMWR)
Long-term efficacy and safety of the single-dose tetravalent Butantan dengue vaccine (Nature Medicine)
Bacterial
Clinical Outcomes in Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae Infection: A Cohort Study (JID)
Duration of therapy for Pseudomonas aeruginosa bacteremia – a post hoc subgroup analysis from the BALANCE randomized controlled trial (CID)
Diagnostic Yield of Tongue Swab- Compared to Sputum-Based Molecular Testing for Tuberculosis in Four High-Burden Countries (CID)
WHO recommends near point-of-care tests, tongue swabs, and sputum poolingfor TB diagnosis (WHO)
Respiratory virus co-infection is a risk factor for adverse outcomes during Staphylococcus aureus bacteraemia (OFID)
Balance Versus Bias: Correcting Misinformation About the 2025 ATS Community-Acquired Pneumonia Guidelines (CID)
Fungal
The Last of US Season 2 (YouTube)
Immunomodulation in the Treatment of Disseminated Coccidioidomycosis (CID)
Parasitic
Comparison of six weeks doxycycline versus six weeks rifampicin or three weeks of the combination of doxycycline plus rifampicin in the treatment of onchocerciasis: a randomized, placebo-controlled, double-blind, phase 2 trial (OFID)
Cutaneous Larva Migrans Within the United States Military Health System – Clinical Presentation and Association with Autochthonous Spread or International Travel (OFID)
Miscellaneous
Distinct prophage infections in colorectal cancer-associated Bacteroides fragilis (Communications Medicine)
Rounding Styles on Inpatient Infectious Disease Consult Services: Impact on Education and Patient-Care Delivery (OFID)
Possible quality indicators for clinical infectious diseases consultations – results from a hybrid Delphi-nominal group approach and scenario study (CMI: Clinical Microbiology and Infections)
Music is by Ronald Jenkees
Information on this podcast should not be considered as medical advice.

On episode #101 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 2/12 – 2/25/26.
Host: Daniel Griffin and Sarah Dong
Subscribe (free): Apple Podcasts, RSS, email
Become a patron of Puscast!
Links for this episode
Viral
Impact of Proviral-DNA M184V/I on 96-Week Outcomes of DTG/3TC Maintenance Therapy: Results From the VOLVER Clinical Trial (CID)
Tecovirimat for the Treatment of Mpox (NEJM)
Bacterial
Multicounty Outbreak of Salmonella Agbeni Linked to Ice in a Cooler at a County Fair — Illinois, August 2024 (CDC: MMWR)
Legionella Pneumonia in the Modern Era: Clinical Features and Predictors of Mortality (CID)
Cefalexin use in UK acute pyelonephritis practice: unaddressed challenges in dosing, breakpoints and clinical evidence (Journal of Antimicrobial Chemotherapy)
Is three really what we need? Relative effectiveness of benzathine penicillin G and doxycycline treatment regimens for late or unknown duration syphilis in 6 United States jurisdictions, 2016–2021 (CID)
Show Me the "Mino:" In Vitro Efficacy of Minocycline on Clinical Gram-Negative Bacterial Isolates (Microbial Drug Resistance)
Initial Vancomycin Taper for the Prevention of Recurrent Clostridioides difficile Infection
(JAMA Network)
Microbial Flora in War Wounds from the Ukrainian Front Line (NEJM)
Fungal
The Last of US Season 2 (YouTube)
Epidemiology of Aspergillosis Diagnoses in U.S. Adults using a National EHR Database, 2013-2023 (OFID)
Parasitic
State-of-the-Art Review: Chagas Disease—an Enduring Challenge (CID)
Autochthonous Rat Lungworm Angiostrongylus cantonensis Infections in Accidental and Definitive Hosts, San Diego, California, USA (Emerging Infectious Diseases)
Miscellaneous
Ancient bacteria strain discovered in ice cave is resistant to some modern antibiotics(CNN)
First genome sequence and functional profiling of Psychrobacter SC65A.3 preserved in 5,000-year-old cave ice: insights into ancient resistome, antimicrobial potential, and enzymatic activities (Frontiers in Microbiology)
Music is by Ronald Jenkees
Information on this podcast should not be considered as medical advice.

On episode #100 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 1/29/26 – 2/11/26.
Host: Daniel Griffin and Sarah Dong
Subscribe (free): Apple Podcasts, RSS, email
Become a patron of Puscast!
Links for this episode
Viral
Type I IFN autoantibodies underlie chikungunya live-attenuated vaccine encephalitis (PNAS)
Dengue Suppression by Male Wolbachia-Infected Mosquitoes (NEJM)
Assessing the impact of SARS-CoV-2 infection and vaccination on fertility and assisted reproductive techniques outcomes: an umbrella review (Vaccine)
Prevalence of CSF HIV VIRAL Escape and Associations With Neurocognitive Outcomes Among HIV-Associated Meningitis Survivors: A Cohort Study (OFID)
Adenoviral Inciting Antigen and Somatic Hypermutation in VITT (NEJM)
Bacterial
Extraintestinal Invasive Escherichia coli Infections in the US (JAMA Network OPEN)
Clinical Manifestations, Long-Term Trends, and Risk Factors for Treatment Failure in Native Vertebral Osteomyelitis: A 26-Year Mayo Clinic Experience (CID)
US Emergency Department Visits forAntibiotic Adverse Drug Events in Children, 2019-2023 (Journal of the Pediatric Infectious Diseases Society)
Fungal
The Last of US Season 2 (YouTube)
Albumin orchestrates a natural host defence mechanism against mucormycosis (Nature)
Pseudo-Outbreak of Purpureocillium lilacinum Skin Infections at a Dermatology Clinic — Washington, 2024 (CDC: MMWR)
Candida auris Testing by the Antimicrobial Resistance Laboratory Network, United States, 2022–2023 (Emerging Infectious Diseases)
Parasitic
Trichinellosis: A zoonosis that still requires vigilance (PLoS Neglected Tropical Diseases)
Trichinellosis after Raw Bear Eyeball Consumption (AJTMH: American Journal of Tropical Medicine and Hygiene)
Moving Scabies Under Video-Dermoscopy (AJTMH: American Journal of Tropical Medicine and Hygiene)
Music is by Ronald Jenkees
Information on this podcast should not be considered as medical advice.

On episode #99 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 1/15/26 - 1/28/26.
Host: Daniel Griffin and Sarah Dong
Subscribe (free): Apple Podcasts, RSS, email
Become a patron of Puscast!
Links for this episode
Viral
Symptomatic and asymptomatic norovirus infections in early life; The PREVAIL Cohort, 2017-2020 (CID)
Bacterial
Xenodiagnosis to search for Borrelia burgdorferi after antibiotic treatment of Lyme disease: a prospective cohort study (CID)
Diagnostic Yield of Repeat Blood Cultures and Risk Factors for Bloodstream Infection in Persistent Febrile Neutropenia (CID)
Methodology Misrepresented: Correcting the Record on the ATS Community-acquired Pneumonia Guideline Process (CID)
Pediatric Infectious Diseases Physicians' Preferences for Management of Clostridioides difficile Infection: An Emerging Infections Network Surve (Journal of the Pediatric Infectious Diseases Society)
Antibiotic Therapy for Uncomplicated AcuteAppendicitis (JAMA)
Fungal
The Last of US Season 2 (YouTube)
Persistence of Symptoms among Commercially Insured Patients with Coccidioidomycosis, United States, 2017–2023 (CDC: Emerging Infectious Diseases)
Ophthalmologic evaluation and clinical outcome in candidemia: a seven-year retrospective multicenter cohort study (OFID)
Parasitic
Postinfectious Syndromes and Long-Term Sequelae after Giardia Infections (CDC: Emergining Infectious Diseases)
Priced Out of Treatment: The Exorbitant Cost of Antiparasitic Drugs in the United States (OFID)
Miscellaneous
All About the AAP Recommended Immunization Schedule (healthychildren.org)
Recommended Childhood and Adolescent Immunization Schedule: United States, 2026: Policy Statement (American Academy of Pediatrics: Pediatrics)
Feeling the Vibes: An Investigation into Resident Antibiotic Prescribing Practices (OFID)
Music is by Ronald Jenkees
Information on this podcast should not be considered as medical advice.