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328: Capturing Shigella With Filopodia
TWiM describes Shigella infection is facilitated by interaction of human enteric α-defensin 5 with a colonic epithelial receptor, and an amino acid change in RNA polymerase that leads to resistance to β-lactams by preventing dysregulation of amino acid and nucleotide metabolism Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson. Subscribe to TWiM (free) on Apple Podcasts, Spotify, Android, RSS, or by email. Become a patron of TWiM. Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Links for this episode National Black HIV/AIDS awareness day (CDC) Shigella infection and human enteric alpha-defensin 5 (Nature Microbio) RNA polymerase amino acid change and resistance to beta-lactams (Cell Rep) Take the TWiM Listener survey! Send your microbiology questions and comments (email or recorded audio) to [email protected]
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327: Freezing and Anti-Freezing With Bacteria
TWiM explains the remarkable abilities of bacterial ice nucleating proteins to promote freezing of water, and cryoprotective proteins produced by worm microbiomes that prevent freezing. Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson. Become a patron of TWiM. Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Links for this episode Worm microbiomes produce crytoprotective proteins (Sci Adv) Biological antifreeze in Antarctic fishes (Sciece) Enhancement of bacterial ice nucleators (PNAS) Take the TWiM Listener survey! Send your microbiology questions and comments (email or recorded audio) to [email protected]
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326: I Have One Word For You: PETase!
TWiM explores the discovery of microbial enzymes, PETases, that can degrade ubiquitous plastics, and how exogenous peptidoglycan is a danger signal to trigger biofilm formation. Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson. Guest Mark O. Martin. Subscribe to TWiM (free) on Apple Podcasts, Spotify, Android, RSS, or by email. Become a patron of TWiM. Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Links for this episode Discovery of PET depolymerases (Science) Exogenous peptidoglycan triggers biofilm formation (Nat Micro) What is a biofilm? (Vimeo) Peptidoglycan as a PAMP/MAMP (Immunol Rev) Light organ formation triggered by peptidoglycan (Science) Take the TWiM Listener survey! Send your microbiology questions and comments (email or recorded audio) to [email protected]
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325: Microbes Making Methane
TWiM reveals that record high atmospheric methane growth has been driven by microbes, and the cecum as an adaptive niche for Salmonella typhi. Hosts: Michael Schmidt, Petra Levin and Michele Swanson. Subscribe to TWiM (free) on Apple Podcasts, Spotify, Android, RSS, or by email. Become a patron of TWiM. Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Links for this episode Why a potent greenhouse gas is rising (WaPo) Microbial emissions drove record high atmospheric methane growth (PNAS) Salmonella biofilm formation in the cecum (mBio) Typhoid Mary (The Collector) Take the TWiM Listener survey! Send your microbiology questions and comments (email or recorded audio) to [email protected]
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324: Back To School for TWiM
From ASMCUE 2024, the conference on undergraduate education, TWiM speaks with Becky, Melanie, and Katriana about their careers and how they use TWiM in undergraduate microbiology education. Hosts: Michael Schmidt and Mark O. Martin Guests: Becky Seipel-Thiemann, Melanie Melendrez-Vallard, and Katriana Popichak Subscribe to TWiM (free) on Apple Podcasts, Spotify, Android, RSS, or by email. Become a patron of TWiM. Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Links for this episode Take the TWiM Listener survey! Send your microbiology questions and comments (email or recorded audio) to [email protected]
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This Week in Microbiology is a podcast about unseen life on Earth hosted by Vincent Racaniello and friends. Following in the path of his successful shows 'This Week in Virology' (TWiV) and 'This Week in Parasitism' (TWiP), Racaniello and guests produce an informal yet informative conversation about microbes which is accessible to everyone, no matter what their science background.

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