MDS Podcast

Dr. Eduardo de Pablo-Fernández is joined by Dr. Susan Fox and Dr. Claudia Trenkwalder to discuss how to improve the current MDS clinical diagnostic criteria for Parkinson's disease.

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Functional dystonia can closely mimic idiopathic dystonia, and objective physiological markers to support the diagnosis are still limited. In this episode, Dr. Michele Matarazzo speaks with Prof. Roberto Eleopra about a pilot study using poly-EMG during a controlled propofol sedation protocol to help differentiate functional from idiopathic dystonia. They discuss the study’s rationale and design, the key findings, and what this approach could (and could not) add to real-world diagnostic workflows in selected complex cases.

Journal CME is available until February 19, 2027



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A young boy presents with exercise-induced episodic gait disturbance. Dr. Shekeeb Mohammad analyses the clinical phenomenology alongside laboratory and neuroimaging findings, systematically exploring the differential diagnosis before arriving at the final diagnosis.

Dr. Mena Farag joins Dr. Eduardo de Pablo-Fernández to discuss how proenkephalin and other biomarkers can help monitor the earliest stages of Huntington's disease decades before the onset of motor symptoms.

Journal CME is available until February 11, 2027



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This episode explores shame as an often-overlooked but impactful non-motor symptom of Parkinson’s disease. Drawing on her team's recent research, Dr. Vanessa Fleury discusses the psychological and clinical determinants of shame, its strong link to quality of life, and why it deserves greater attention in routine care. The conversation highlights how recognizing and addressing shame may open new avenues for more holistic, patient-centered management.

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