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This Week in Startups

Podcast This Week in Startups
Jason Calacanis
Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, ...

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  • Twilio Bets Small, DeepSeek Scares & the GameOn Fraud | E2076
    This Week in Startups is brought to you by… Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up: fitbod.me/TWIST Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up. Today’s show: Jason and Alex cover Twilio’s team size compression, DeepSeek’s scary good AI for only $6M and the GameOn fraud saga that sounds too crazy to be true. Timestamps: (0:00) Alex and Jason kick off the show (6:27) Rundown of potential topics (7:10) Twilio's team size strategy and AI's impact on workforce (9:40) Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up: fitbod.me/TWIST (14:52) Entrepreneurship in the AI era and automation concerns (19:30) Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST (22:49) Meta's investment in data centers and surplus compute power (26:36) Technology’s potential to solve humanity’s problems (30:12) Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up. (32:01) Empathy for workers displaced by automation (34:11) DeepSeq's role in reducing AI industry costs (37:27) Game On startup fraud case and due diligence in startups (53:13) Venture capital's role in startup oversight (55:36) OpenAI's Operator announcement and AI autonomy risks Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Thank you to our partners: (9:40) Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up: fitbod.me/TWIST (19:30) Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST (30:12) Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up. Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason’s suite of newsletters: https://substack.com/@calacanis Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
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  • Created By Humans | Sila’s Battery Evolution | E2075
    This Week in Startups is brought to you by… Gusto. Get three months free when you run your first payroll at http://gusto.com/twist Netsuite. Download the CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist Atlassian. Head to Atlassian.com/Startups/TWiST to see if you qualify for 50 free seats for 12 months. Today’s show: Alex covers The Stargate Project, other hot news items, and two great interviews. Created By Humans’ Co-founder Trip Adler talks about the future of copyrights and AI. Gene Berdichevsky, Co-founder and CEO of Sila, discusses the future of batteries and our clean energy future. Timestamps: (0:00) Alex kicks off the show. (1:22) Introduction to Mistral's IPO, Anthropic's funding, and Project Stargate (6:01) Market reactions and AI funding landscape (10:19) Gusto. Get three months free when you run your first payroll at http://gusto.com/twist (11:35) Tripp Adler discusses AI in literature and Created by Humans (16:20) Authors' concerns and AI companies' reactions (19:42) Netsuite. Download the CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist (20:58) Tripp Adler on AI, copyright, and the future of authorship (27:47) Human-created content symbol and synthetic vs. human data (29:52) Atlassian. Head to Atlassian.com/Startups/TWiST to see if you qualify for 50 free seats for 12 months. (34:08) Gene Berdichevsky on Sila's battery technology and Titan Silicon anodes (41:29) Battery tech's role in industry transformation and consumer devices (48:25) The impact on renewable energy and grid storage (53:02) Hard tech challenges, fundraising, and IPO considerations (56:38) Netflix's quarterly earnings and tech market forecasts Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Check out: Created by Humans: Website: https://www.createdbyhumans.ai/ X: https://x.com/createdbyhumans Follow Trip: X: https://x.com/tripadler LinkedIn: https://www.linkedin.com/in/tripadler/ Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Thank you to our partners: (10:19) Gusto. Get three months free when you run your first payroll at http://gusto.com/twist (19:42) Netsuite. Download the CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist (29:52) Atlassian. Head to Atlassian.com/Startups/TWiST to see if you qualify for 50 free seats for 12 months. Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason’s suite of newsletters: https://substack.com/@calacanis Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
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  • Trump, Memecoins, and What to Expect from the New Administration | E2074
    Today’s show: Jason and Alex explore America's fascination with billionaires and self-made figures, touching on recent events in Washington, DC, and the tech industry's political influence. They discuss Gen X's rising political power, tech CEOs' prominence at inaugurations, and critique Democrats' tech policies. The conversation covers economic factors in elections, like inflation and abortion rights, COVID's origins, immigration policy, and foreign policy. AI regulation under Biden and Trump's economic strategies, including crypto regulations, are debated. They also discuss Trump's impact on M&A, antitrust laws, and the startup ecosystem, with insights on tech IPOs and tax policy. * Timestamps: (0:00) Jason and Alex kick off the show. (1:06) Diving into recent DC events and tech's political role (3:13) Gen X's rising political influence and tech CEOs' prominence at inauguration (7:00) Discussion on tech founders' importance and criticism of Democrats' tech stance (10:17) PrizePicks. TWiST listeners, download the app today and use code TWIST to get $50 instantly after you play your first $5 lineup! Go to: https://prizepicks.onelink.me/LME0/TWIST PrizePicks - Run your game. (11:35) Economic factors influencing elections: Inflation and abortion rights (17:15) COVID origins investigation and executive orders affecting tech (19:58) OpenPhone. TWiST listeners can get 20% off your first 6 months at https://openphone.com/twist (21:25) Steve Bannon, JD Vance, and immigration policy discussions (23:20) US potential territory expansion and foreign policy (30:23) LinkedIn Jobs. TWiST listeners can post their first job for free at https://www.linkedin.com/twist (32:13) Trump's economic strategies, legacy, and US energy production (41:23) AI and drone technology: Regulation and countermeasures (51:05) Crypto's economic value, personal freedoms, and investment risks (1:01:27) Entrepreneur wellness, Trump's EV policies, and state vs. federal regulation (1:04:23) New admin’s influence on M&A, antitrust laws, and startup ecosystems (1:09:08) Upcoming tech IPOs, tax policy, and regulatory capture discussion * Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp * Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm * Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis * Thank you to our partners: (10:17) PrizePicks. TWiST listeners, download the app today and use code TWIST to get $50 instantly after you play your first $5 lineup! Go to: https://prizepicks.onelink.me/LME0/TWIST PrizePicks - Run your game. (19:58) OpenPhone. TWiST listeners can get 20% off your first 6 months at https://openphone.com/twist (30:23) LinkedIn Jobs. TWiST listeners can post their first job for free at https://www.linkedin.com/twist * Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland * Check out Jason’s suite of newsletters: https://substack.com/@calacanis * Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com * Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
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  • TikTok Ban, Data Centers in Space… and What's a Vector? | E2073
    Today’s show: Alex sits down with two CEOs from companies freshly added to the TWIST500. We get a masterclass from Bob van Luijt of Weaviate, on vector databases helping AI and LLMs do what they do. An then Philip Johnston from Lumen Orbit explains his vision of building data centers in space! * Timestamps: (0:00) Alex kicks off the show. (0:58) Supreme Court ruling on TikTok and key market numbers (3:49) Interview introduction with Weaviate and Lumen Orbit CEOs (4:06) Deep dive into vector databases with Weaviate's Bob van Luijt. (8:23) Lemon. TWiST listeners get 15% off your first 4 weeks of developer time at https://Lemon.io/twist (11:35) Exploring deep learning, vector indexing, and Weaviate's open-source significance (18:03) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist ⁠today. (19:32) Discussion on vector databases use cases and retrieval augmented generation (RAG) (27:17) Weaviate's business model, revenue streams, and growth (28:12) Vanta. TWiST listeners automate your SOC2 and get $1,000 off at http://www.vanta.com/twist (32:52) The future of AI, agentic architectures, and enterprise adoption (40:50) Lumen Orbit's vision for space-based data centers (42:54) Philip Johnston on the technical aspects of Lumen Orbit (49:12) Satellite demonstrators, technology challenges, and VC interest (53:26) Addressing chip obsolescence and cost advantages in space (56:21) Deployment strategies and competition in the space data center market (1:00:12) Strategies for staying ahead of competition and future plans for Lumen Orbit * Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Check out Weaviate: https://weaviate.io/ Check out Lumen Orbit: https://www.lumenorbit.com/ * Follow Bob: X: https://x.com/bobvanluijt LinkedIn: https://www.linkedin.com/in/bobvanluijt * Follow Philip: X: https://x.com/johnstonphil LinkedIn: https://www.linkedin.com/in/johnstonphilip/ * Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm * Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis * Thank you to our partners: (8:23) Lemon. TWiST listeners get 15% off your first 4 weeks of developer time at https://Lemon.io/twist (18:03) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist (28:12) Vanta. TWiST listeners automate your SOC2 and get $1,000 off at http://www.vanta.com/twist * Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland * Check out Jason’s suite of newsletters: https://substack.com/@calacanis * Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com * Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
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  • What’s Going On With Google Gemini Deep Research? | E2072
    This Week in Startups is brought to you by… PrizePicks. TWiST listeners, download the app today and use code TWIST to get $50 instantly after you play your first $5 lineup! Go to: https://prizepicks.onelink.me/LME0/TWIST PrizePicks - Run your game. Coda. TWiST listeners get 6 months at https://www.Coda.io/twist Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up: fitbod.me/TWIST Today’s show: Jason and Alex interview Aarush Selvan, lead PM at Google Gemini Deep Research, and discuss their groundbreaking work. They also took a moment to cover TikTok’s dire situation and AI investment to start the year. (0:00) Show Teaser (1:26) Jason Calacanis shares his Japan skiing experience (6:18) Arush Selvan from Google Gemini team background discussion (9:26) PrizePicks. TWiST listeners, download the app today and use code TWIST to get $50 instantly after you play your first $5 lineup! Go to: https://prizepicks.onelink.me/LME0/TWIST PrizePicks - Run your game. (14:23) Deep research demonstration and server resource usage (19:42) Coda. TWiST listeners get 6 months at https://www.Coda.io/twist (22:11) Google's business model and AI-generated research reports (29:55) Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up: fitbod.me/TWIST (32:00) Personalized data integration and content permissions in AI tools (34:22) Differentiation and hallucinations in AI-generated content (44:11) Business models for AI search engines and OpenAI's new task feature (54:30) Synthesia's AI-generated video tool demo and privacy in biometric payments (59:36) Investments in AI companies and TikTok's potential ban (1:04:17) Chinese government influence and US rule of law in tech (1:07:29) Irony of migrating to Little Red Book and upcoming inauguration (1:08:02) Staying updated with This Week in Startups Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Check out Google Gemini Deep Research: https://blog.google/products/gemini/google-gemini-deep-research/ Check out Open AI Scheduling: https://help.openai.com/en/articles/10291617-scheduled-tasks-in-chatgpt Check out Synthesia: https://www.synthesia.io/ Follow Aarush: X: https://x.com/AarushSelvan LinkedIn: https://www.linkedin.com/in/aarush-selvan-3a376a8b/ Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Thank you to our partners: (9:26) PrizePicks. TWiST listeners, download the app today and use code TWIST to get $50 instantly after you play your first $5 lineup! Go to: https://prizepicks.onelink.me/LME0/TWIST PrizePicks - Run your game. (19:42) Coda. TWiST listeners get 6 months at https://www.Coda.io/twist (29:55) Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up: fitbod.me/TWIST Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason’s suite of newsletters: https://substack.com/@calacanis Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
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Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.
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