American History Tellers

On Valentine’s Day 1929, seven men were gunned down in a Chicago garage in an attack that stunned the nation. Photographs of the bloody scene appeared on front pages across the country, and the public reacted with horror. Even in Chicago—a city hardened by daily gang violence—the message was clear: this was different.
City officials were under intense pressure to respond, and suspicion quickly fell on the city’s most powerful gang leader, Al Capone. But proving who ordered the hit would be far more difficult than expected. And as investigators struggled to build their case, the fallout from the massacre would change Chicago—and Capone’s fate—forever.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In 1920, a young Al Capone arrived in Chicago looking for a fresh start, and his timing couldn’t have been better. That same year, Prohibition outlawed the manufacture and sale of alcohol, turning America’s thirst into a criminal gold rush. Chicago quickly became the epicenter of bootlegging, and Capone was determined to seize the moment and make himself rich beyond imagination. But the city was already crowded with ambitious gangsters chasing the same prize. As rival bootleggers carved up territory, Chicago descended into a violent turf war that would reshape the criminal underworld.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In the early 1950s, Jonas Salk and Albert Sabin were in a race to develop a vaccine against polio. While Salk’s killed-virus vaccine was the first to be distributed, Sabin continued working to perfect his own approach. In the end, Sabin’s oral polio vaccine—made from a weakened live virus—proved easier to administer and was ultimately distributed far more widely, though his name never achieved the same recognition. In this episode, Lindsay is joined by epidemiologist and oral historian Karen Torghele. Her book Albert Sabin: The Life of a Polio Vaccine Pioneer is due to be published by Yale University Press in June of 2026.
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In April 1954, a group of first graders lined up in the gymnasium of an elementary school in McLean, Virginia for the start of the Salk polio vaccine trials. In an era before widespread federal government involvement in public health, the National Institute of Infantile Paralysis executed an unprecedented experiment involving nearly 2 million children and tens of thousands of doctors, nurses, and volunteers. It was the largest peacetime mobilization in American history.
While scientists evaluated the results, Americans waited anxiously to find out whether the vaccine was safe and effective, putting an end to 40 years of fear. But in the spring of 1955, a shocking revelation would bring the vaccination program to a sudden halt.
Be the first to know about Wondery’s newest podcasts, curated recommendations, and more! Sign up now at https://wondery.fm/wonderynewsletter
Listen to American History Tellers on the Wondery App or wherever you get your podcasts. Experience all episodes ad-free and be the first to binge the newest season. Unlock exclusive early access by joining Wondery+ in the Wondery App, Apple Podcasts or Spotify. Start your free trial today by visiting wondery.com/links/american-history-tellers/ now.
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

By the late 1940s, the National Institute of Infantile Paralysis had raised millions of dollars to pay for patient care and laboratory research. But polio cases were reaching record levels, and scientists were no closer to a cure. Frustrated by the slow progress, Basil O’Connor resolved to recruit fresh talent to the cause. He soon found what he was looking for in a young and energetic researcher named Jonas Salk.
In 1951, Salk began testing a killed virus polio vaccine on monkeys in his Pittsburgh lab. His research soon put him at odds with the leading polio scientist Albert Sabin, who wanted his own live virus vaccine formula to prevail. As their rivalry escalated, Salk prepared to take the risky step of testing his vaccine on human subjects.
Be the first to know about Wondery’s newest podcasts, curated recommendations, and more! Sign up now at https://wondery.fm/wonderynewsletter
Listen to American History Tellers on the Wondery App or wherever you get your podcasts. Experience all episodes ad-free and be the first to binge the newest season. Unlock exclusive early access by joining Wondery+ in the Wondery App, Apple Podcasts or Spotify. Start your free trial today by visiting wondery.com/links/american-history-tellers/ now.
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.