with @guywuolletjr @eddylazzarin @smc90"Which blockchain should I build in?" Is a very top of mind question for builders in web3, including  for people coming into the space for the first time -- but also relevant to anyone interested in tech innovation, tech stacks, and the evolution of infrastructure. So how does one decide among all the chain choices out there, particularly given how fast-moving the crypto and web3 space is? Things are constantly changing, things are still being built, and there's no one size fits all answer...So in this episode, we -- a16z crypto’s Guy Wuollet, and CTO Eddy Lazzarin, in conversation with host Sonal Chokshi -- tease apart all the tangled threads and nuances of the topic. In the first third of the discussion, we sketch out the overall landscape, why it matters, quick definitions. Then, we focus on common/ frequently asked questions, specific tradeoffs, and a framework for deciding which chain -- including discussing different technical specs, as well as other dimensions such as: community, marketing & ecosystem support, security, custody, programming languages, and much, much more. resources related to or mentioned in this episode:Programming Languages & Crypto (2023) with Sam Blackshear, Eddy Lazzarin, Noah Citron, Sonal ChokshiThe Four Horsemen of Centralization (2018) by Ali YahyaDecentralization for web3 Builders: Principles, Models, How (2022) by Miles JenningsNetwork Effects, Origin Stories, and the Evolution of Tech (2018), with Brian Arthur, Marc Andreessen, and Sonal Chokshi  [see also this paper referenced]None of the following should be taken as investment, legal, business, or tax advice. Please also see a16z.com/disclosures for important information -- including a link to a list of our investments -- since we are investors in some of the companies mentioned in this episode. 

with @aeyakovenko @alive_eth @guywuolletjr @smc90This all-new deep-dive, hallway-style chat features a16z crypto general partner Ali Yahya and deal team partner Guy Wuollet, in conversation with Solana co-founder and Solana Labs CEO Anatoly Yakovenko --  who also worked at Qualcomm for over a decade, where he was a senior engineer and engineering manager among other things. The first half of the episode is a discussion/ debate blockchain architectures -- including of course Solana & Ethereum, the themes of monolithic vs. modular, et cetera -- but really is about what are the tradeoffs, and what should one optimize for (or not!), depending on what you’re building, and to make crypto happen at scale (now and in the future). The second half of the episode covers company-, community-, and ecosystem-building -- including discussing the nuances of leadership in open source; and wherefore messiahs/ prophets?! -- as well as touching on engineering hiring, devrel (developer relations), governance; the Solana phone, and some of the Solana backstory as well. What are the differences between hardware and software innovation? And how does innovation play out, in theory versus practice? These are the throughlines of this episode... For more on some of the topics discussed, see also: a high-level overview of topics including VDFs, defined (with Joe Bonneau)resources on all things VDFs /verifiable delay functions on a16zcrypto.com, including:an introduction to verifiable delay functions (from a16z crypto research partner Joe Bonneau)our episode on AI & crypto (with Ali Yahya)our discussion on the evolution of programming languages & crypto (including Move's Sam Blackshear)As a reminder: none of this should be taken as investment, legal, business, or tax advice; please see a16z.com/disclosures for more important information -- including a link to a list of our investments.

with @davidmarcus @smc90This wide-ranging conversation covers company building, big to small -- including what cadence and when is the right "time" to ship; the relationship between centralization, decentralization, platforms, and financial freedom; moving from web2 to web3 in both crypto AND payments... as well as why bitcoin, views on remote work, and much much more. Our guest is David Marcus, CEO and co-founder of Lightspark; Marcus was also a co-creator of Diem (aka Libra and Novi, the cryptocurrency project initiated by Facebook). Before that, he was vice president of messaging products there, where he ran the Facebook Messenger unit; and prior to joining Facebook, Marcus was the former president of PayPal (which had acquired his previous startup).  This episode begins with an interview just to help kick things off and then features a rich set of questions from the audience -- as this originally took place live on stage at our Crypto Startup School 2023. As a reminder: none of this should be taken as investment, legal, business, or tax advice; please see a16z.com/disclosures for more important information -- including a link to a list of our investments.related readings:Regulate apps, not protocols series (2022-2023) - Miles Jennings et al, a16z crypto)What it will take to create the next great Silicon Valleys (2014) - Marc Andreessen (Politico, a16z)Why bitcoin matters (2014) - Marc Andreeessen (NYT, a16z) When one app rules them all: The case of WeChat and Mobile in China (2015) - Connie Chan (a16z)  

with @alive_eth @danboneh @smc90This week's all-new episode covers the convergence of two important, very top-of-mind trends: AI (artificial intelligence) & blockchains/ crypto. These domains together have major implications for how we all live our lives everyday; so this episode is for anyone just curious about, or already building in the space. The conversation covers topics ranging from deep fakes, bots, and the need for proof-of-humanity in a world of AI; to big data, large language models like ChatGPT, user control, governance, privacy and security, zero knowledge and zkML; to MEV, media, art, and much more. Our expert guests (in conversation with host Sonal Chokshi) include: Dan Boneh, Stanford Professor (and Senior Research Advisor at a16z crypto), a cryptographer who’s been working on blockchains for over a decade and who specializes in cryptography, computer security, and machine learning -- all of which intersect in this episode;Ali Yahya, general partner at a16z crypto, who also previously worked at Google -- where he not only worked on a distributed system for a fleet of robots (a sort of "collective reinforcement learning") but also worked on Google Brain, where he was one of the core contributors to the machine learning library TensorFlow built at Google.The first half of the hallway-style conversation between Ali & Dan (who go back together as student and professor at Stanford) is all about how AI could benefit from crypto, and the second half on how crypto could benefit from AI... the thread throughout is the tension between centralization vs. decentralization.  So we also discuss where the intersection of crypto and AI can bring about things that aren't possible by either one of them alone...pieces referenced in this episode/ related reading:The Next Cyber Reasoning System for Cyber Security (2023) by Mohamed Ferrag, Ammar Battah, Norbert Tihanyi, Merouane Debbah, Thierry Lestable, Lucas CordeiroA New Era in Software Security: Towards Self-Healing Software via Large Language Models and Formal Verification (2023) by  Yiannis Charalambous, Norbert Tihanyi, Ridhi Jain, Youcheng Sun, Mohamed Ferrag, Lucas CordeiroFixing Hardware Security Bugs with Large Language Models (2023) by Baleegh Ahmad, Shailja Thakur, Benjamin Tan, Ramesh Karri, Hammond PearceDo Users Write More Insecure Code with AI Assistants? (2022) by Neil Perry, Megha Srivastava, Deepak Kumar, Dan BonehAsleep at the Keyboard? Assessing the Security of GitHub Copilot's Code Contributions (2021) by Hammond Pearce, Baleegh Ahmad, Benjamin Tan, Brendan Dolan-Gavitt, Ramesh KarriVoting, Security, and Governance in Blockchains (2019) with Ali Yahya and Phil Daian    As a reminder: none of the following should be taken as investment, legal, business, or tax advice; please see a16z.com/disclosures for more important information -- including to a link to a list of our investments – especially since we are investors in companies mentioned in this episode.

with @mclader @smc90 In this wide-ranging conversation, Uniswap Labs COO Mary Catherine (aka MC) Lader discusses the challenges -- and opportunities -- of decentralized finance (DeFi); business strategy (& competition) in a world of open source; product vs. protocol innovation... as well as organizational structure & collaboration, hiring, metrics, community engagement, app store policies, decentralization, and much, much more. The conversation -- based on an interview with host Sonal Chokshi and founder Q&A live from a16z crypto Startup School earlier this year -- also covers how to make decisions on what to innovate on or not; how to move from  idea and vision to business; and the transition overall from traditional finance/ tradfi. Before joining Uniswap Labs (which contributes to Uniswap, a protocol for trading and automated liquidity provision on Ethereum) -- Lader was a managing director at BlackRock (and chief operating officer of the firm’s digital wealth business and head of its climate tech business); was formerly a fintech entrepreneur; and began her career as an investment analyst at Goldman Sachs. ---As a reminder: none of the following should be taken as investment, legal, business, or tax advice; please see a16z.com/disclosures for more important information -- including a link to a list of our investments.