59 afleveringen
- I caught up with @baelentina_ and @lukeigel to get a vibe check on SF so far in 2026 and explain why Corgi-posting proliferated across the timeline (i'm sorry).
Also you might have noticed that MOTS looks somewhat polished?? Well Luke's product @trykino kind of changed my life.
Watch on X; listen on Apple Podcasts or Spotify.
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Blackbox AI is an AI-powered software development platform designed to help developers and non-developers build, test, fix, and deploy code and applications faster and with less manual effort than traditional tools.
Capy is the better way to build and run AI workflows. It’s a multiplayer IDE for agents, automations, and intelligent systems. Create agents, automate tasks, and connect your data into systems that actually get work done, all in one place.
Circleback makes meetings memorable. From detailed notes to action item tracking and searchable meetings. With powerful automations and integrations, Circleback helps you capture knowledge, stay organized, and turn conversations into meaningful work. Use this link to get 60 days free.
Langfuse is the #1 open-source LLMOps platform that helps developers trace, evaluate, and optimize LLM applications from prototype to production. With observability, prompt management, experiments, and evaluations in one integrated platform, Langfuse makes it easier to build reliable AI products that continuously improve over time. - In today's extra I caught up with @maxmarchione to get a vibe check on peptides (they kind of fell off), get the FDA peptide panel update and talk about each other's stacks and skincare and such.
Watch on X; listen on Apple Podcasts or Spotify.
Sponsors
Blackbox AI is an AI-powered software development platform designed to help developers and non-developers build, test, fix, and deploy code and applications faster and with less manual effort than traditional tools.
Superpower is a modern health platform that gives you a complete, data-driven view of your body in one place. From advanced blood testing and biomarker tracking to personalized insights and action plans, Superpower helps you understand what’s actually going on under the hood and what to do about it. Built for people who want to take their health seriously without guessing, spreadsheets, or fragmented care.
Capy is the better way to build and run AI workflows. It’s a multiplayer IDE for agents, automations, and intelligent systems. Create agents, automate tasks, and connect your data into systems that actually get work done, all in one place.
Circleback makes meetings memorable. From detailed notes to action item tracking and searchable meetings. With powerful automations and integrations, Circleback helps you capture knowledge, stay organized, and turn conversations into meaningful work. Use this link to get 60 days free.
Langfuse is the #1 open-source LLMOps platform that helps developers trace, evaluate, and optimize LLM applications from prototype to production. With observability, prompt management, experiments, and evaluations in one integrated platform, Langfuse makes it easier to build reliable AI products that continuously improve over time. - There has been a lot of discussion of the SF housing crisis on the timeline recently so I brought on @sdamico and @Noahpinion to break down how we got here while we cooked some steaks.
Finally MOTS gets political.
Watch on X; listen on Apple Podcasts or Spotify.
Sponsors
Blackbox AI is an AI-powered software development platform designed to help developers and non-developers build, test, fix, and deploy code and applications faster and with less manual effort than traditional tools.
Superpower is a modern health platform that gives you a complete, data-driven view of your body in one place. From advanced blood testing and biomarker tracking to personalized insights and action plans, Superpower helps you understand what’s actually going on under the hood and what to do about it. Built for people who want to take their health seriously without guessing, spreadsheets, or fragmented care.
Capy is the better way to build and run AI workflows. It’s a multiplayer IDE for agents, automations, and intelligent systems. Create agents, automate tasks, and connect your data into systems that actually get work done, all in one place.
Circleback makes meetings memorable. From detailed notes to action item tracking and searchable meetings. With powerful automations and integrations, Circleback helps you capture knowledge, stay organized, and turn conversations into meaningful work. Use this link to get 60 days free.
Langfuse is the #1 open-source LLMOps platform that helps developers trace, evaluate, and optimize LLM applications from prototype to production. With observability, prompt management, experiments, and evaluations in one integrated platform, Langfuse makes it easier to build reliable AI products that continuously improve over time. - I caught up with @Celesteamadon to chat about a few things SF dating:
- Single until series B
- The state of dating apps
- Men in SF
I was also put on the spot with how I used to date (trick question I was terrified).
Watch on X; listen on Apple Podcasts or Spotify.
Sponsors
Blackbox AI is an AI-powered software development platform designed to help developers and non-developers build, test, fix, and deploy code and applications faster and with less manual effort than traditional tools.
Superpower is a modern health platform that gives you a complete, data-driven view of your body in one place. From advanced blood testing and biomarker tracking to personalized insights and action plans, Superpower helps you understand what’s actually going on under the hood and what to do about it. Built for people who want to take their health seriously without guessing, spreadsheets, or fragmented care.
Capy is the better way to build and run AI workflows. It’s a multiplayer IDE for agents, automations, and intelligent systems. Create agents, automate tasks, and connect your data into systems that actually get work done, all in one place.
Circleback makes meetings memorable. From detailed notes to action item tracking and searchable meetings. With powerful automations and integrations, Circleback helps you capture knowledge, stay organized, and turn conversations into meaningful work. Use this link to get 60 days free.
Langfuse is the #1 open-source LLMOps platform that helps developers trace, evaluate, and optimize LLM applications from prototype to production. With observability, prompt management, experiments, and evaluations in one integrated platform, Langfuse makes it easier to build reliable AI products that continuously improve over time. The Permanent Underclass and the Future of Human Enhancement, with Dr Mike Israetel
13-07-2026 | 1 u. 15 Min.I took Dr Mike to the park to see the dogs and talk about classic San Francisco topics such as:
- the permanent underclass
- artificial intelligence
- human enhancement and peptides
Everybody has been waiting to hear what the bodybuilders have to say about all this.
Watch on X; listen on Apple Podcasts or Spotify.
Sponsors
Blackbox AI is an AI-powered software development platform designed to help developers and non-developers build, test, fix, and deploy code and applications faster and with less manual effort than traditional tools.
Superpower is a modern health platform that gives you a complete, data-driven view of your body in one place. From advanced blood testing and biomarker tracking to personalized insights and action plans, Superpower helps you understand what’s actually going on under the hood and what to do about it. Built for people who want to take their health seriously without guessing, spreadsheets, or fragmented care.
Capy is the better way to build and run AI workflows. It’s a multiplayer IDE for agents, automations, and intelligent systems. Create agents, automate tasks, and connect your data into systems that actually get work done, all in one place.
Circleback makes meetings memorable. From detailed notes to action item tracking and searchable meetings. With powerful automations and integrations, Circleback helps you capture knowledge, stay organized, and turn conversations into meaningful work. Use this link to get 60 days free.
Langfuse is the #1 open-source LLMOps platform that helps developers trace, evaluate, and optimize LLM applications from prototype to production. With observability, prompt management, experiments, and evaluations in one integrated platform, Langfuse makes it easier to build reliable AI products that continuously improve over time.
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