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Shirtloads of Science

Dr Karl Kruszelnicki
Shirtloads of Science
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  • Innovative Nanotechnology for Cancer Detection with Dr. Renee Goreham (450)
    In this episode, we chat with Dr. Renee Goreham, a physicist and nanotechnologist at the University of Newcastle, and passionate science communicator. Renee is an experimental physicist exploring how our breath could hold the key to detecting lung cancer early—by identifying specific proteins as biomarkers. We also delve into her PhD student's exciting research into a new red-light laser diagnostic tool for breast cancer. Along the way, Renee breaks down the basics of cell biology and shares her inspiring, non-linear journey through physics, nanotech, and beyond. A brilliant example of multidisciplinary science in action. Follow Renee on TikTok: @dr_renee_goreham
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  • Gene Therapy & Rare Diseases with Assoc. Prof Leszek Lisowski (449)
    In this episode, we speak with Associate Professor Leszek Lisowski, Head of the Translational Vectorology Unit at the Children's Medical Research Institute (CMRI), about the cutting-edge world of gene therapy. He explains how viral vectors are engineered to deliver life-saving treatments for rare genetic diseases - many of which are so uncommon, they're only known by the name of the affected gene. Despite being often overlooked, genetic diseases impact 10% of adults and 30% of children in hospitals. Leszek sheds light on the challenges of diagnosis, the promise of emerging genetic testing, and how his work is paving the way for more accurate, effective therapies. Linkedin: Children's Medical Research Institute, Leszek Lisowski Facebook: @jeansforgenes Instagram: @jeansforgenesau
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  • The Brain's Energy Bill: From Childhood to Old Age with Assoc. Prof Sharna Jamadar (448)
    In this episode, we're joined by Associate Professor Sharna Jamadar, a cognitive neuroscientist at Monash University, to explore how the brain uses energy, and how that changes across the lifespan. Did you know that a 10-year-old's brain uses over 50% of the body's total energy, compared to just 20% in adults? We dive into why younger brains work harder, the role of synaptic pruning and proliferation, and how the brain's organisation impacts cognitive efficiency. We also touch on the importance of glucose metabolism and its connection to age-related disorders like Alzheimer's. A fascinating look at the energy demands of our most complex organ! Bluesky: @SharnaJamadar Linkedin: Sharna Jamadar www.sharnajamadar.com Email: [email protected]
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  • Onionlike Layers of Exploding Stars with Prof. Geraint Lewis (447)
    My go-to guy for all cosmic things Prof. Geraint Lewis, astrophysicist at the University of Sydney, returns to unpack a fascinating New York Times article on a newly observed "onionlike" space explosion that may reveal a new type of supernova. We dive into what actually happens when a star dies, the onion-layer buildup of elements through nuclear fusion, and how these cataclysmic blasts forge the building blocks of life on Earth. Plus, we explore what this might mean for the ultimate fate of our own Sun. www.geraintflewis.com/ Linkedin: Geriant Lewis
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  • The Aftermath of Cosmic Collisions with Prof. Geraint Lewis (446)
    In this episode, friend of the show Geriant Lewis, Professor of Astrophysics at the Sydney Institute for Astronomy within the University of Sydney, joins us to unpack a fascinating New Scientist article theorising on how a strange line of dwarf galaxies may have formed.  We explore how high-speed collisions between dwarf galaxies can scatter gas and stars across space, sometimes giving rise to entirely new tidal galaxies. Geraint explains the latest thinking on where these dwarf galaxies come from and how these cosmic smash-ups might even shed light on one of the biggest mysteries in physics: the true nature of dark matter. www.geraintflewis.com/ Linkedin: Geriant Lewis Bluesky: cosmic_horizons
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Dr Karl's a curious optimist – a great combination for a science lover. Join him and his guests for weird facts, amazing conversation and remember, it's never too late for a happy childhood. https://drkarl.com/
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