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- High FSH? Low AMH? Diminished ovarian reserve or POI? Failed IVF or told donor eggs are your only option? Book a free Functional Fertility Second Opinion before your next fertility decision → fabfertile.com
You've been diagnosed with premature ovarian insufficiency and told your ovaries aren't responding as expected. Maybe you've had a canceled IVF cycle, retrieved very few eggs, or been advised to consider donor eggs.
You're trying to understand what this means and whether there's anything else worth investigating before making your next decision.
When I was diagnosed with POI at 28, I didn't get a second opinion. I went on to have both of my children through donor eggs. Years later, I discovered non-celiac gluten sensitivity, gut issues, and chronic stress that hadn't been part of my fertility conversations.
I can't say those issues caused my POI. But I wish someone had helped me understand my broader health alongside the diagnosis.
What if your POI diagnosis is important information, but there are still health patterns that deserve attention?
In this episode, I share three areas our team considers when reviewing cases involving POI, low AMH, high FSH, and failed IVF: gut and immune health, thyroid and autoimmune patterns, and chronic stress and nervous system regulation.
We explore what these patterns may reveal about your broader health and the questions they can help you bring to your medical team.
In this episode:
What POI means and why it isn't simply another name for menopause
Why AMH, FSH and follicle count don't explain every aspect of your reproductive health
How digestive symptoms and nutrient absorption fit into a broader health review
Why thyroid function and autoimmune history deserve attention
What iron, B12, folate and homocysteine may reveal about nutritional status
Why sleep, under-fueling, excessive exercise and chronic stress deserve context
Where nervous system support fits alongside fertility treatment
Why your bone and cardiovascular health matter after a POI diagnosis
Questions to ask before deciding on another IVF cycle or donor eggs
You may have POI, and donor eggs may still be the right option for you. Investigating your broader health doesn't promise to reverse the diagnosis or change your fertility outcome.
You don't have to put IVF on hold to investigate your health. Both can happen in parallel.
The goal is to understand your results, identify what else deserves attention, and make your next fertility decision with more clarity. Your health matters whichever path you choose.
FREE RESOURCE: THE ULTIMATE GUIDE TO GETTING PREGNANT WITH LOW AMH AND HIGH FSH
If you're navigating low AMH, high FSH, or diminished ovarian reserve, this free guide walks you through important fertility markers, nutrition and lifestyle strategies, and what to consider as you plan your next steps.
Get your free copy here.
FUNCTIONAL FERTILITY SECOND OPINION
Book with your partner if you're trying to conceive together, and upload your labs and test results to our secure portal before the call.
We review what you already have, your fertility history, previous IVF response, and the health of both partners to identify questions that may not have been explored and discuss potential next steps.
Book here
ABOUT THE HOST
I'm Sarah Clark, founder of Fab Fertile and host of Get Pregnant Naturally, a podcast with over one million downloads. For almost 12 years, my team and I have worked with couples navigating low AMH, diminished ovarian reserve, high FSH, POI, recurrent pregnancy loss, and failed IVF.
We look across fertility history, previous treatment, bloodwork, functional testing, and the health of both partners to identify patterns that may not have been explored. We work alongside your fertility clinic, not instead of it.
Sarah Clark, founder of Fab Fertile, host of Get Pregnant Naturally (1M+ downloads), and author of Fabulously Fertile. - Book your free 45-minute Functional Fertility Second Opinion: https://fabfertile.com/pages/book
You've been through IVF, maybe more than once, and your doctor says your TSH is normal. But has anyone looked at your full thyroid picture?
In this episode, I'm sharing why TSH alone may not tell the whole story, especially if you're navigating low AMH, high FSH, diminished ovarian reserve, POI, or failed IVF.
You'll learn:
What TSH, Free T4, Free T3, and thyroid antibodies can tell us
What research says about thyroid autoimmunity, IVF outcomes, and miscarriage
Why thyroid medication may be necessary, but other health concerns can still deserve attention
How gut health, nutrient deficiencies, blood sugar, and nervous system regulation fit into our functional fertility approach
Your reproductive health doesn't exist in a silo. We look for patterns across your symptoms, health history, and testing while working alongside your fertility specialist.
I'm Sarah Clark, founder of Fab Fertile, author of Fabulously Fertile, and host of Get Pregnant Naturally, a podcast with over one million downloads.
My functional fertility team specializes in helping couples navigating low AMH, high FSH, diminished ovarian reserve (DOR), premature ovarian insufficiency (POI), recurrent miscarriage, and failed IVF. We use functional lab testing, targeted nutrition and lifestyle strategies, and nervous system regulation to identify patterns that may have been missed.
We work alongside your medical team, not instead of them.
Free Thyroid and Fertility Guide: https://fabfertile.com/pages/thyroid-guide
Subscribe to Get Pregnant Naturally and share this episode with someone navigating failed IVF. - Low AMH? Diminished ovarian reserve or POI? Failed IVF or told donor eggs are your only option? Book a free Functional Fertility Second Opinion before your next fertility decision → fabfertile.com
You have low AMH or diminished ovarian reserve. You've gone through IVF stimulation, but only one or two follicles developed. Maybe your cycle was canceled before egg retrieval.
Now you're wondering whether mini IVF, lower medication doses, or a different protocol could give you a better response.
But you're also frustrated. You've already invested time, money, and hope into IVF, and you still don't understand why your ovaries aren't responding.
What if changing your IVF protocol isn't the only thing worth investigating?
In this episode, we explore why poor ovarian response deserves a closer look at your overall health and how a functional fertility approach can work alongside your fertility clinic.
In this episode:
Why low AMH and diminished ovarian reserve can make IVF stimulation challenging
What to consider when only one or two follicles develop, or your IVF cycle is canceled
Why mini IVF, lower medication doses or a different stimulation protocol may be worth discussing with your fertility specialist
How thyroid function, nutrient deficiencies and blood sugar regulation fit into your fertility assessment
Why digestion, inflammation, sleep and chronic stress deserve attention
Why the male partner's health matters, even when the focus has been on your ovarian response
How to investigate your health while continuing to explore IVF treatment options
You may decide to try another IVF protocol. Or you may need time to consider other fertility options.
You don't have to put IVF on hold to investigate your health. Both can happen in parallel.
The goal is to make your next decision with more clarity and fewer unanswered questions.
FUNCTIONAL FERTILITY SECOND OPINION
Book with your partner if you're trying to conceive together, and upload your labs and test results to our secure portal before the call.
We review what you already have, your fertility history, previous IVF response, and the health of both partners to identify questions that may not have been explored and discuss potential next steps.
Book here
ABOUT THE HOST
I'm Sarah Clark, founder of Fab Fertile and host of Get Pregnant Naturally, a podcast with over one million downloads. For almost 12 years, my team and I have worked with couples navigating low AMH, diminished ovarian reserve, high FSH, POI, recurrent pregnancy loss, and failed IVF.
We look across fertility history, previous treatment, bloodwork, functional testing, and the health of both partners to identify patterns that may not have been explored. We work alongside your fertility clinic, not instead of it.
Sarah Clark, founder of Fab Fertile, host of Get Pregnant Naturally (1M+ downloads), and author of Fabulously Fertile. - Low AMH? Diminished ovarian reserve or POI? Failed IVF or told donor eggs are your only option? Book a free Functional Fertility Second Opinion before your next fertility decision → fabfertile.com
You've been told your AMH is too low. Your FSH is too high. Your IVF cycle didn't work.
And now donor eggs are being recommended.
Maybe donor eggs are the right next step for you. But before making that decision, have you been given the full picture of what's happening with your fertility?
Was the recommendation based mainly on your AMH and FSH? Has anyone reviewed what happened during your IVF cycles, including follicle response, fertilization, and embryo development?
And has anyone looked beyond your ovaries?
Donor eggs can be a wonderful path to parenthood. This isn't about ruling them out. It's about understanding your options and making a decision with fewer unanswered questions.
In this episode:
Why low AMH and high FSH don't tell the whole story about your fertility
What to ask when donor eggs are recommended after failed IVF
Why your previous IVF response, fertilization, and embryo development matter
Why the male partner needs to be investigated beyond a normal semen analysis, including sperm DNA fragmentation
What may still be worth reviewing, including thyroid and autoimmune patterns, metabolic health, inflammation, gut health and the nervous system
How to determine whether further investigation could meaningfully inform your next fertility decision
Why being informed about donor eggs doesn't mean you have to decide immediately
You may ultimately choose donor eggs. Or you may decide there are still questions worth exploring with your fertility team.
Either way, you deserve to understand why a particular path is being recommended.
FUNCTIONAL FERTILITY SECOND OPINION
Book with your partner and upload your labs and testing into our secure portal before the call. If you've done testing in the last three months, we won't automatically ask you to repeat it.
We review what you already have, your fertility history, previous IVF response and the health of both partners to identify questions that may not have been explored and discuss potential next steps.
Book here
ABOUT THE HOST
I'm Sarah Clark, founder of Fab Fertile and host of Get Pregnant Naturally, a podcast with over one million downloads. For almost 12 years, my team and I have worked with couples navigating low AMH, diminished ovarian reserve, high FSH, POI, recurrent pregnancy loss, and failed IVF.
We look across fertility history, previous treatment, bloodwork, functional testing, and the health of both partners to identify patterns that may not have been explored. We work alongside your fertility clinic, not instead of it.
Sarah Clark, founder of Fab Fertile, host of Get Pregnant Naturally (1M+ downloads), and author of Fabulously Fertile. Tried Functional Medicine for Low AMH or Failed IVF? What Might Still Be Missing
12-10-2026 | 13 Min.Low AMH? Diminished ovarian reserve or POI? Failed IVF or recurrent loss? Book a free Functional Fertility Second Opinion before your next fertility decision → fabfertile.com
You've done the stool test. You've worked on your gut, changed your diet and taken the supplements. You've addressed your thyroid, hormones and inflammation.
So when someone asks whether anyone has looked deeper into your health, your answer is:
I've already done functional medicine.
But did your practitioner specialize in low AMH, diminished ovarian reserve, POI, recurrent pregnancy loss or failed IVF?
And did they connect what they found to your fertility history, IVF response, and the health of both partners?
Doing functional medicine and having a complex fertility case investigated aren't necessarily the same thing.
In this episode:
Why general functional medicine may miss patterns that matter in low AMH, DOR, POI, recurrent loss and failed IVF
Why more testing and more supplements aren't necessarily the answer
What may still be worth investigating, including inflammation, autoimmune and thyroid patterns, the nervous system, gut health and vaginal microbiome
Why his side matters beyond a normal semen analysis, including sperm DNA fragmentation
How your IVF history, embryo development and recurrent losses become part of the investigation
What to ask about the work you've already done before another IVF cycle
You're not starting over. You're figuring out what hasn't been connected yet.
CHAPTERS
00:00 I've already done functional medicine
02:10 General functional medicine versus complex fertility cases
03:40 High achieving, hypervigilant and the nervous system
04:30 His side beyond a normal semen analysis
10:50 Your fertility history, IVF response and recurrent loss
FUNCTIONAL FERTILITY SECOND OPINION
Book with your partner and load your labs and testing into our secure portal before the call. If you've done testing in the last three months, we won't ask you to repeat it. We look at what you already have, your fertility history and the health of both partners, see what's been missed, and give you a plan to put it all together.
Book here
ABOUT THE HOST
I'm Sarah Clark, founder of Fab Fertile and host of Get Pregnant Naturally, a podcast with over one million downloads. For almost 12 years, my team and I have worked with couples navigating low AMH, diminished ovarian reserve, high FSH, POI, recurrent pregnancy loss and failed IVF.
We look across fertility history, previous treatment, bloodwork, functional testing, and the health of both partners to identify patterns that may not have been explored. We work alongside your fertility clinic, not instead of it.
Sarah Clark, founder of Fab Fertile, host of Get Pregnant Naturally (1M+ downloads), and author of Fabulously Fertile.
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Get Pregnant Naturally is the podcast for women and couples facing low AMH, high FSH, failed IVF, miscarriage, premature ovarian insufficiency (POI), diminished ovarian reserve (DOR), or a donor egg recommendation, and who are not ready to accept that recommendation before the full picture has been investigated.
Hosted by Sarah Clark, founder of Fab Fertile, author of Fabulously Fertile, and host of a podcast with over one million downloads, Get Pregnant Naturally offers a functional fertility second opinion. Each week, Sarah walks through the lab work most fertility clinics do not run: gut microbiome, food sensitivity, vaginal microbiome, nutrigenomics, HTMA, DUTCH, full thyroid panel, the iron panel, and inflammation markers, alongside nervous system work. Inside the Fab Fertile program, the full team works with each couple. On the podcast, Sarah brings you what she sees across more than a decade of cases.
This podcast is for the woman who heard donor eggs and walked out, wondering what was missed. The woman whose REI looked at her AMH, her FSH, and her antral follicle count, and stopped there. We work alongside your medical team, not instead of them. The decision still belongs to you. The investigation should happen before the decision.
Subscribe for weekly episodes on what your fertility clinic may not have tested before the next recommendation gets made.
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- Veel andere app-functies


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