Depresh Mode with John Moe
John Moe, Maximum Fun

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AI Chatbots Destroyed His Reality. Dr. Jeremy Heffner Explains Why He Believed Them.
07-09-2026 | 1 u. 3 Min.Dr. Jeremy Heffner was a highly educated, high achieving surgeon. Not the kind of person one would expect to slide down an AI chatbot-generated rabbit hole, lose touch with reality, and give credence to the bot’s suggestion that he was one of the three smartest humans ever. But that’s what happened. The bots also told him there was a 70% chance AI would end the world and only Jeremy could save it. His experience, chronicled in his new book, Proof of the Impossible. Jeremy joins us to talk about the PTSD treatment he had received before this untethering, the long climb back to reality, and why he still uses AI chatbots.
Thank you to all our listeners who support the show as monthly members of Maximum Fun.
Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!
Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.
Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.
Help is available right away.
The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK
Crisis Text Line: Text HOME to 741741.
International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines
Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh
Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh- Cameron Esposito has many titles: hugely successful standup comedian, actor in television and film, writer, podcast host. After a recent rehab stay led to a mental health diagnosis, she has realized that she’s also a person with bipolar disorder, type II. Cameron has a new special, Four Pills, that’s part stand-up comedy and part reflection on the circumstances that led to this discovery as well as thoughts on what life as a treated person for bipolar will mean going forward. Cameron Esposito joins us for a very funny and deeply personal conversation about mental health, medication, comedy, and the road ahead.
Thank you to all our listeners who support the show as monthly members of Maximum Fun.
Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!
Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.
Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.
Help is available right away.
The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK
Crisis Text Line: Text HOME to 741741.
International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines
Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh Cat Grief is Real. So is Human Grief. We’re Underestimating and Misunderstanding Both.
24-08-2026 | 1 u. 4 Min.Bay Area journalist s.e. smith thinks the high school goths were right: we should be talking about death all the time. It’s underdiscussed for something that will literally affect us all. And in that silence, they say, things get worse: the topic becomes less approachable, inevitable periods of grief can become more chaotic and disruptive, and the actual pain of losing your person or cat or dog can become harder to process. s.e. went out and talked to dozens of death-related people - death doulas, psychologists, funeral directors - to see what we could do about this topic to find some peace to rest in long before we actually have to rest in peace. They offer some insight, also, into the ways capitalism tries to steal your grief and leave you more messed up as a result.
Then we check in with friend of the show Emily Nagoski, author of hugely acclaimed book about sex Come As You Are. She tells us about her recent bout of agoraphobia and how she did her best to fight it off so she could see a Bigfoot musical.
Thank you to all our listeners who support the show as monthly members of Maximum Fun.
Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!
Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.
Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.
Help is available right away.
The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK
Crisis Text Line: Text HOME to 741741.
International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines
Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepreshOh, It’s Autism, Mary H.K. Choi Learned at 43. Okay, She Thought, That Explains a Lot.
17-08-2026 | 1 u. 7 Min.Mary H.K. Choi compares living with her brain to just not understanding the operating system on a computer. She didn’t know if this was a result of trauma and neglect in her childhood, the experience of being parentified as a child, grief after the death of her father, or what. So she spent decades of effort and piles of dollars to figure it out. She did cognitive behavioral therapy, internal family systems therapy, “heroic doses of psilocybin under the watchful gaze of a shaman”, and anything else she could try. Finally, under the burnout and fear from covid, her functionality began to fall apart and she looked into the possibility of autism spectrum disorder as a possible culprit. And ding ding ding goes the slot machine, first a self-diagnosis from online resources and then a confirmed clinical diagnosis. Looking back now, she sees some of the clues, including a lack of empathy for others and the act of “performing competency”, that make more sense now. Mary offers insight on the long path to figuring out one’s mind and what she’s doing now that she has some answers.
Thank you to all our listeners who support the show as monthly members of Maximum Fun.
Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!
Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.
Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.
Help is available right away.
The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK
Crisis Text Line: Text HOME to 741741.
International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines
Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepreshMargaret Glaspy Ends Her Instagram Addiction and Sings From Her Original Thought
10-08-2026 | 1 u. 2 Min.Margaret Glaspy compares the experience she was having on Instagram to being lightly punched in the gut, over and over, for a very long time. Like it’s not like being hit hard, just a little tap of something negative with each update you read, each comparison made, each distancing away from actual humanity and toward the simulated reality the platform presents. So she quit social media. Which was hard because it was an actual addiction. And then she wrote and recorded her new album, I Am Both, which just came out. It’s a remarkable work as Margaret leaned on her own mind, her own thoughts and memories and experiences. The California-raised, Brooklyn-based musician was inspired by the clear voice and perspective of heroes like Bob Dylan, Joni Mitchell, and John Steinbeck. It’s a candid interview that just might inspire you to make a big change of your own.
Thank you to all our listeners who support the show as monthly members of Maximum Fun.
Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!
Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.
Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.
Help is available right away.
The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK
Crisis Text Line: Text HOME to 741741.
International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines
Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh
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Over Depresh Mode with John Moe
Join host John Moe (The Hilarious World of Depression) for honest, relatable, and, yes, sometimes funny conversations about mental health. Hear from comedians, musicians, authors, actors, and other top names in entertainment and the arts about living with depression, anxiety, and many other common disorders. Find out what they’ve done to address it, what worked, and what didn’t. Depresh Mode also features useful insights on mental health issues with experts in the field. It’s honest talk from people who have been there and know their stuff. No shame, no stigma, and more laughs than you might expect.
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Depresh Mode with John Moe
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